The prevalence of pneumococcal carriage in Serbia during COVID Serbia pneumococcal Vaccines Pneumococcus Antimicrobialresistance COVID19 Vaccination immunization Elderly Antibioticresistance PLOSONE
By Dr. Sanchari Sinha Dutta, Ph.D.Oct 17 2022Reviewed by Benedette Cuffari, M.Sc. In a recent PLoS One journal study, scientists explore the prevalence of Streptococcus pneumoniae carriage and its antimicrobial resistance patterns in adults aged 50 years and older during the coronavirus disease 2019 pandemic. Herein, a low prevalence of Spn carriage was observed, in addition to identifying four vaccine-related serotypes.
A high prevalence of Spn carriage has been observed in children under two years; however, the pathogen can also infect adults of any age. The age distribution of the disease may vary between countries, depending on the socioeconomic status of the affected individual and environmental factors. Study design The study included 521 participants with or without upper respiratory tract infection symptoms who visited an outpatient facility during the second year of the COVID-19 pandemic.
Molecular serotyping of the 16 Spn-positive samples identified four vaccine-specific serotypes and two non-vaccine serotypes. The remaining ten samples were non-typeable isolates of pneumococci. Spn antibiotic-resistance patterns All Spn-positive samples were subjected to antibiotic-resistance testing. The highest resistance of Spn was observed against erythromycin and tetracycline.
Study significance The study provides an overview of Spn carriage during the COVID-19 pandemic in middle-aged and older adults residing in Serbia. Based on the study estimates, Serbia has a low prevalence of Spn carriage. All six Spn serotypes identified in the study were obtained from nasopharyngeal samples.
Danmark Seneste Nyt, Danmark Overskrifter
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