Exploring clinical characteristics and outcomes of hospitalized COVID-19 patients UvA_Amsterdam COVID19 SARSCoV2 ClinicalCharacteristics Hospitalization
By Tarun Sai LomteNov 24 2022Reviewed by Aimee Molineux In a recent study published in Open Forum Infectious Diseases, researchers described the clinical characteristics and outcomes of patients hospitalized with coronavirus disease 2019 in the Netherlands.
About the study In the present study, researchers described COVID-19 characteristics and outcomes in hospitalized patients and analyzed the association between new COVID-19 therapies and some clinical outcomes in the Netherlands. Data from the CovidPredict database and the Dutch National Intensive Care Evaluation registry were used.
Baseline patient characteristics and outcomes were compared using one-way analysis of variance , Kruskal-Wallis, and Chi-squared tests for parametric, non-parametric, and categorical data, respectively. Ward and ICU patients were separately analyzed. The primary and secondary outcomes were examined using Cox regression.
The proportion of males admitted to hospital wards and the median age of ward patients decreased over COVID-19 waves. Likewise, crude in-hospital mortality for patients admitted to wards decreased from 21% in the first wave to 15% in the fourth wave. Hydroxychloroquine and lopinavir/ritonavir were almost exclusively used during the first wave, and remdesivir was used in the second wave.
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