UCLan academics make stronger connections between gum disease and Alzheimer’s disease

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UCLan academics make stronger connections between gum disease and Alzheimer’s disease
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Researchers at the uclan School of Dentistry were the first to report the link between gum disease and Alzheimer’s disease. Now progress is being made in making much stronger connections between gum disease in the mouth and deteriorating brain function

Researchers at the School of Dentistry, University of Central Lancashire were the first to report the link between gum disease and Alzheimer’s disease.Now two new studies from the same research group at the School of Dentistry demonstrate that progress is being made in making much stronger connections between gum disease in the mouth and deteriorating brain function.

These new studies go a step further in exploring how gum disease and its bacterial proteins can potentially contribute to the formation of lesions on the brain. The second study, published in the Journal of Alzheimer’s Disease Reports, looks at the way the gingipains enzyme, released by the bacterium, can contribute to the formation of amyloid-beta plaques – another of the lesions, alongside the tangles, which form on the brains of those suffering from Alzheimer’s.

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