Scientists led by a team from Duke-NUS Medical School have identified three distinct serotypes of SARS-related coronaviruses, marking the need for vaccines that can provide broad-spectrum protection against them.
, suggests that immunity from vaccination or prior infection by one serotype may be ineffective against another or against new variants. This is because while the viruses of different serotypes can be genetically similar, they function and affect our immune system differently.
Previous analyses had been conducted using samples from only animals or vaccinated people. These were therefore not as accurate or relevant in determining how different viruses affect the human immune system. The scientists determined that one serotype comprises the SARS-CoV-1 virus . SARS-CoV-2 and its delta and beta variants make up the second serotype. While the omicron subvariants originated from SARS-CoV-2, they have evolved functionally to become a distinct group and make up the third serotype. This is supported by data showing that serum from people infected with SARS-CoV-2 was not able to neutralize viruses from its omicron subvariants or even from SARS-CoV-1.
"The strong selective pressure driven by population immunity favors the emergence of new virus variants. Omicron variants are distinct from their ancestral SARS-CoV-2 virus and can be regarded as a distinct group in the context of antibody immune responses. This implies that pre-existing SARS-CoV-2 immunity is insufficient to prevent current and future infections," said co-first author Dr.
Danmark Seneste Nyt, Danmark Overskrifter
Similar News:Du kan også læse nyheder, der ligner denne, som vi har indsamlet fra andre nyhedskilder.
Small study suggests long COVID may affect more people than previously thoughtMillions of Americans were exposed to SARS-CoV-2, the virus that causes COVID-19, early in the pandemic but could not get diagnosed due to testing limitations. Many of those people developed a post-viral syndrome with symptoms similar to those of long COVID. In a new study of a small group of those people, their immune response shows that 41% had evidence of SARS-CoV-2 exposure. The study is published in Neurology Neuroimmunology & Neuroinflammation.
Læs mere »
KTM’s 390 and 125 Duke models return with refreshed design and equipmentBoth models gain a range of updated parts.
Læs mere »
The women scientists who took India into spaceThe BBC meets three Indian female scientists who prove that rocket science is not a male preserve.
Læs mere »
Scientists find way to 'press self-destruct button' in gastric cancer associated with Epstein-Barr VirusNow, scientists at The Wistar Institute have discovered a potential target for gastric cancers associated with Epstein-Barr Virus; study results were published in the journal mBio.
Læs mere »
Scientists genetically decode rare kidney diseaseWhen Dr. Bodo Beck first saw the three children of a family who had fled Syria sitting in his consultation room at University Hospital Cologne, the human geneticist was surprised. His genetic analysis diagnosed Bartter syndrome type 3, but never before had he seen such severe joint changes in patients with this rare disease.
Læs mere »
Scientists confirm the one type of person who wouldn't last on another planetIt's a classic personality type.
Læs mere »