A team of UC Davis and University of Oxford researchers have developed an innovative tool: SparkMaster 2.
Reviewed by Lily Ramsey, LLMSep 1 2023 The open-source software allows scientists to analyze normal and abnormal calcium signals in cells automatically.
Jakub Tomek, the first author of the research article, is a Sir Henry Wellcome Fellow in the Department of Physiology, Anatomy and Genetics at the University of Oxford. He spent his fellowship year at UC Davis, working with Distinguished Professor Donald M. Bers. At the Bers Lab at UC Davis, Tomek discussed analysis tools with Christopher Y. Ko, an assistant project scientist. They identified the need for better, more user-friendly software, which led to the development of SparkMaster 2.
Although much of the new interface resembles the original SparkMaster, they started from scratch for the programming. Using Python, an open-source programming language that has grown in popularity, they were able to utilize many existing tools and libraries to create the unique features they wanted. Bers anticipates the primary users of the software will be scientists who study calcium in muscle. "But it may be useful for researchers who study other cell types, such as neurons, that exhibit local calcium events that are important in regulating cellular function," Bers said.
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