The prebiotic resistant starch could play an important role in the treatment of non-alcoholic fatty liver disease (NAFLD) in the future.
Reviewed by Danielle Ellis, B.Sc.Sep 5 2023 Initial indications suggest that a specially adapted diet with resistant starch not only positively influences the intestinal microbiome but also leads to an alleviation of the disease.
"We found out that the participants in the study benefited from a resistant starch diet, as the accumulation of fat in the diseased liver was reduced. Furthermore, we observed an increase in certain types of bacteria in the gut of the participants; these bacteria positively influenced fat reduction and transport in the liver.
The team led by Gianni Panagiotou, Weiping Jia, Yueqiong Ni, and Huating Li examined serum and fecal samples from 200 participants over a period of four months. They found that the level of "Bacteroides stercoris", in particular, increases significantly the more severe the disease is. "In our study, we found Bacteroides stercoris occurred in less amount in test persons after eating 40 grams of resistant starch per day", says co-corresponding author Huating Li.
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