Alternatives to the laboratory mouse

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Alternatives to the laboratory mouse
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Researchers are looking at whales, sparrows and large dogs

possible that at this point you, the reader, are thinking that a greatly enhanced lifespan would be there for the taking had you only had the good luck or foresight to have been born a laboratory mouse. So many things, after all, seem to extend their life’s lease. If so, you should learn from the scepticism of Steven Austad of the University of Alabama, Birmingham.

This scepticism may, in part, come from the fact that Dr Austad took an unusually long and circuitous route to the lab. His first degree was in English literature; as well as making an abortive attempt to write the great American novel he has enjoyed employment as a taxi driver, a newspaper reporter and an animal trainer. The last job provoked an interest in zoology that led to academia.

With a maximum recorded lifespan of just over 120 years, human beings are at the upper end of the animal longevity scale. But there are a few that outdo them. At an estimated 200 years, bowhead whales are thought to be the longest-living mammals. Greenland sharks can manage double that. Giant tortoises are well-known multicentenarians.

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