Researchers administered the jab to a group for one year and compared results to those given a placebo
Semaglutide not only helped patients in the trial lose weight and eased heart failure symptoms, but also improved their tolerance for exercise
The trial – the findings of which were presented at the ESC Congress in Amsterdam on Friday – included 529 patients, all of whom had a body mass index of more than 30, as well as heart failure symptoms and psychical limitations.One group was given a once-weekly semaglutide 2.4 mg – also known as Wegovy – for one year while the other was given a placebo.
He said Wegovy “produced large improvements in symptoms, physical limitations and exercise function, reduced inflammation, and resulted in greater weight loss and fewer serious adverse events as compared with placebo”. “We believe that these findings should also change the nature of the conversation about the role of obesity in HFpEF, as the Step-HFpEF results clearly indicate that obesity is not simply a comorbidity in patients with HFpEF but a root cause and a target for therapeutic intervention.”
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