Viable monkeypox virus found in nearly all environmental samples from patient's room in first week of infection medrxivpreprint Monkeypox Infection Transmission Virus
By Neha MathurSep 20 2022Reviewed by Aimee Molineux In a recent study posted to the medRxiv* pre-print server, researchers investigated the presence of viable monkeypox virus in a room occupied by an infected male patient admitted to the National Centre for Infectious Diseases , Singapore.
About the study In the present study, researchers longitudinally sampled the air, surfaces, water, and dust in an airborne infection isolation room occupied by an MPXV patient who presented with skin lesions and fever. The room was cleaned daily with 10,000 parts-per-million bleach and had 12 uni-directional high-efficiency particulate air filter changes per hour. The team performed environmental sampling on infection days 7, 8, 13, and 21.
Study findings Related StoriesThe researchers detected MPXV DNA in the patient's nasopharyngeal swab and peri-anal lesions on day 5 of infection when he got admitted to the hospital. The frequency of his skin lesions was the highest on the buttocks, followed by the back and extremities , but they resolved after eight days of infection. The patient got discharged from the hospital on day 23 of the MPXV infection.
The environmental contamination reduced from the second week of infection when the patient stopped developing new skin lesions. This finding highlighted the importance of disinfection of the surfaces of chairs, toilets, and floors and taking precautions when handling linens. The researchers found MPXV material only in particles of >4 μm sizes, which nullified the possibility that MPXV was transmitted via breathing or talking in this case.
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