Ultra-high-resolution MRI reveals migraine brain changes rsna
region called the centrum semiovale," said study co-author Wilson Xu, an M.D. candidate at Keck School of Medicine of the University of Southern California in Los Angeles."These changes have never been reported before."
Punctate deep white matter hyperintensities on sagittal T2-weighted MRI, more prominent in the frontal lobes. Migraine-free control without punctate WMH. Credit: RSNA and Wilson Xu Study participants included 10 with chronic migraine, 10 with episodic migraine without aura, and five age-matched healthy controls. All patients were between 25 and 60 years old. Patients with overt cognitive impairment, brain tumor, prior intracranial surgery, MRI contraindications and claustrophobia were excluded from the study.areas of the brain. White matter hyperintensities—lesions that"light up" on MRI—were measured using the Fazekas scale.
"We studied chronic migraine and episodic migraine without aura and found that for both types of migraine, perivascular spaces were bigger in the centrum semiovale," Xu said."Although we didn't find any significant changes in the severity of white matter lesions in patients with and without migraine, these white matter lesions were significantly linked to the presence of enlarged perivascular spaces.
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