The potential influence of pre-existing parasitic infections on COVID-19 morbidity

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The potential influence of pre-existing parasitic infections on COVID-19 morbidity
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The potential influence of pre-existing parasitic infections on COVID-19 morbidity PLOSNTDs disease infection parasite COVID19 coronavirus covid morbidity

By Dr. Sanchari Sinha Dutta, Ph.D.Oct 13 2022Reviewed by Danielle Ellis, B.Sc. A study recently published in PLOS Neglected Tropical Diseases has explored the association between the prevalence of pre-existing parasitic diseases and outcomes of coronavirus disease 2019 at the national level.

Several hypotheses have been put forward to explain this noticeable difference in COVID-19 outcomes between countries. Several causative factors have been identified, including socio-demographic and geographical factors, the prevalence of comorbidities, climatic conditions, as well as the possibility of underreporting.

Of various human-infecting parasites, only Schistosoma spp., soil-transmitted helminthiases, and Plasmodium spp. were considered in the study. Regarding socioeconomic factors, country-level healthcare infrastructure, income, and overall standard of living were considered. Moreover, the country-level population density, population density in urban regions, and average surface temperature were considered geographic factors.

The assessment of the relationship between one independent and one dependent variable revealed that countries with a high prevalence of parasitic diseases have a lower incidence of COVID-19.

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