Much like young children who swiftly acquire languages in their early years, our visual system also has a 'critical period' during the first few years of life where rapid development occurs. After this time, changes become more difficult, following the old adage, 'You can't teach an old dog new tricks.'
Researchers have devised a first-of-its-kind setup for delivering complex visual stimuli within a rodent MRI scanner to understand adult plasticity in the brain’s visual pathways. Credit: Hedi Young
The study's central question, therefore, was to explore whether the adult mammalian brain still possesses the ability to reorganize its As Noam Shemesh points out, the journey towards these revelations was fraught with technical hurdles."Joana Carvalho, our lead researcher, faced numerous challenges and even doubts from some of the world's leading labs who thought her endeavor was impossible. But Joana's perseverance paid off. Without her resolve and creativity, we never would have reached this point."
Having surmounted these challenges, the researchers set out to explore the adult brain's adaptability to visual signals. They used a model in which rodents are born and raised in the dark until adulthood, well past the critical period of plasticity. Consequently, the brains of these animals had not yet undergone the key processes required for visual specialization.
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