Super ager brains contain 'super neurons' northwesternu sfnjournals
"The remarkable observation that super agers showed larger neurons than their younger peers may imply that large cells were present from birth and are maintained structurally throughout their lives," said lead author Tamar Gefen, an assistant professor of psychiatry andat Northwestern University Feinberg School of Medicine."We conclude that larger neurons are a biological signature of the SuperAging trajectory.
"To understand how and why people may be resistant to developing Alzheimer's disease, it is important to closely investigate the postmortem brains of super agers," Gefen said."What makes super agers' brains unique? How can we harness their biologic traits to help elderly stave off Alzheimer's disease?"
In the study, scientists show that super agers harbor large, healthier neurons in layer II of the entorhinal cortex compared to their same-aged peers, individuals with early stages of Alzheimer's disease and even individuals 20 to 30 years younger. They also showed that these large layer II neurons were spared from the formation of tau tangles.
For reasons that remain unknown, cell populations in the entorhinal cortex are selectively vulnerable to tau tangle formation during normal aging and in early stages of Alzheimer's.appears to be a characteristic marker of the disease," Gefen said.
Danmark Seneste Nyt, Danmark Overskrifter
Similar News:Du kan også læse nyheder, der ligner denne, som vi har indsamlet fra andre nyhedskilder.
Here's a fan trailer for a Super Mario 'remake' with Chris PrattBefore the Mario movie comes out, why not enjoy this trailer for a super realistic Super Mario Bros remake starring Chris Pratt?
Læs mere »
Nottinghamshire police officer lands national football boss roleFormer Women's Super League player Jemma Connor-Iommi will lead the national police football team.
Læs mere »
Chelsea come from behind to beat West Ham in WSLChelsea recover from an early setback to beat West Ham in the Women's Super League at Kingsmeadow.
Læs mere »
Plans to axe Super League relegation for top clubs'Category A' Super League clubs would not be able to be relegated under IMG recommendations, following the sport's 'most comprehensive' consultation.
Læs mere »
WRC New Zealand: Tanak fires first salvo in opening super specialHyundai’s Ott Tanak has grabbed an early lead at Rally New Zealand after winning a tricky opening World Rally Championship super special stage from M-Sport’s Craig Breen.
Læs mere »