Study finds the majority of post-vaccination monkeypox infections occur within 2 weeks of receiving the first dose of MVA-BN

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Study finds the majority of post-vaccination monkeypox infections occur within 2 weeks of receiving the first dose of MVA-BN
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Study finds the majority of post-vaccination monkeypox infections occur within 2 weeks of receiving the first dose of MVA-BN howardbrownhc JAMANetwork vaccination monkeypox virus vaccine infection

By Bhavana KunkalikarOct 5 2022Reviewed by Danielle Ellis, B.Sc. In a recent study published in JAMA Network, researchers described the human monkeypox virus infection after vaccination with the modified Vaccinia Ankara-Bavarian Nordic vaccine.

About the study The present study described monkeypox infections observed following a single dose of MVA-BN. From the electronic medical record , all instances of monkeypox-positive cases during the study period were retrieved. The EMR and a study of a statewide computerized database for the exchange of immunization records were then used to determine the patient's vaccination status.

Results During the trial period, 7,339 people at HBH received their first dosage of MVA-BN, while 400 patients tested positive for monkeypox. Among 90 individuals who tested monkeypox-positive a minimum of one day after immunization, 73.5% displayed viral loads less than 200 copies/mL, 91% were cisgender, and 37.8% had HIV.

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