Group A streptococci are fairly common bacteria that can cause, among other things, strep throat or impetigo.
Reviewed by Megan Craig, M.Sc.Aug 17 2023 However, if the bacteria become invasive, the situation can become very dangerous. In this case, the name sometimes changes to murder bacteria or flesh-eating bacteria and can give rise to life-threatening conditions such as blood poisoning and septic shock, or soft tissue infections that may make an amputation necessary.
Our hypothesis was that it depends on an interplay between the genes in people and bacteria. Very little was previously known about how different variants of genes in the bacteria and our immune system interact and affect the outcome of infectious diseases.
Related StoriesThe study also shows how the severity of an infection depends on the interplay between one gene – STING – in our immune system and a bacterial enzyme found in the bacteria that have become more prevalent in the western world since the 1980s. This explains why some people are more severely affected than others.
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