A stem cell patch developed by USC researchers for patients with macular degeneration will soon be tested in a phase 2b clinical trial.
This latest milestone in the patch's development was made possible by a combined $21 million in support from a state organization, a nonprofit foundation and the university. Last month, the California Institute for Regenerative Medicine awarded an estimated $12.4 million to the USC-supported startup Regenerative Patch Technologies to test the safety and efficacy of the patch for treating advanced dry age-related macular degeneration, also known as "geographic atrophy.
I want to thank USC President Carol L. Folt for supporting this important research, as well as USC Research and Innovation for all the work they did to make this possible. I would also like to thank The Marcus Foundation for their generous support after a thorough review process." "We are thrilled to support this critically important medical innovation by fostering the university's ongoing technology transfer and commercialization efforts through faculty partnerships with small businesses," said Ishwar K. Puri, senior vice president for USC Research and Innovation.
The disease affects a vital group of cells: retinal pigment epithelium cells. When healthy, these cells enable photoreceptor cells of the retina to detect light. With geographic atrophy, RPE cells degenerate over time. This can lead to photoreceptor loss, impaired vision and, for many, blindness, forcing some patients to lose their independence.
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