Relatively short-term use of immunosuppressant medications to control an inflammatory disease was not associated with an increased risk of later developing cancer, according to new research led by scientists at the University of Pittsburgh and Mass Eye and Ear, a member of the Mass General Brigham health care system, and published in the journal BMJ Oncology.
Relatively short-term use of immunosuppressant medications to control an inflammatory disease was not associated with an increased risk of later developing cancer, according to new research led by scientists at the University of Pittsburgh and Mass Eye and Ear, a member of the Mass General Brigham health care system, and published in the journalThe findings should provide reassurance to patients and clinicians who may hesitate to prescribe the medications because they are known to increase the...
The new findings were from the Systemic Immunosuppressive Therapy for Eye Diseases Cohort, which began two decades ago when principal investigator John Kempen, M.D., Ph.D.
The research team tracked each participant for an average of 10 years after they took immunosuppressant medications, or for a similar amount of time for those not taking immunosuppression, to see if they ever developed cancer. Four different categories of immunosuppressants—TNF-inhibitors, antimetabolites, alkylating agents and calcineurin inhibitors—were covered by the study, with some patients taking more than one type. Patients were on the medications for a median of one year.
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