Recently published in the journal American Journal of Physiology, a Brazilian study demonstrated for the first time that survivors of severe COVID-19 infections may have elevated muscle sympathetic nerve activity (MSNA) in response to mental stress.
To measure the effects of stress, patients and the control group were exposed to a 3-minute activity in which slides were projected in front of them and the image changed every 2 seconds, accompanied by conflicting sounds that were delivered through headphones. At the end of the analysis, it was concluded that all participants noticed a similar increase in the level of stress, but that in patients who had COVID-19, some physiological reactions were discrepant.
The authors also measured vascular responses to this stress induction and analyzed blood flow, vascular function, and mean arterial pressure across each participant's forearm. The analysis showed that the first two aspects were attenuated in COVID-19 patients, being more than 100% lower when compared to the control group, while mean arterial pressure was similar in all individuals.
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