Millions of women suffer the disease every year.
typically have higher blood sugar levels
During the trial, 98% of women remained in the trial until delivery, with 88% completing the 12-week post-delivery follow up assessment – 4.9% of women discontinued the medication due to side effects. Delivery occurred at the same mean gestational age – 39.1 weeks – in both groups, and there was no evidence of any increase in preterm birth – defined as birth before 37 weeks – among those who received metformin.Infants born to mothers who received metformin weighed, on average, 113g less at birth, with significantly fewer infants classified as large at birth, or weighing over 4kg.There was a slight reduction in infant length – 0.
Fidelma Dunne, professor of medicine at University of Galway, will present the results at the 59th annual meeting of the European Association for the Study of Diabetes in Hamburg today. ‘A previous trial compared metformin to insulin and found it to be effective, yet concerns remained, especially regarding preterm birth and infant size.’
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