New research has uncovered 'direct evidence that the SARS-CoV-2 spike protein is toxic to heart muscle cells,' according to its lead author.
The first line of defence against the invasion of the SARS-CoV-2 pathogen is natural immunity, and heart muscle cells have their own immune machinery - but in the case of COVID-19 infections the immune response"may also impair heart muscle cell function and even lead to cell death and heart failure," Dr Lin said.
But unlike with SARS-CoV-2, the NL63 spike protein does not trigger the natural immune response in heart muscle cells which can cause so much damage to the organ."The fact that the SARS-CoV-2 spike protein is activating the natural immune response may explain the high virulence compared to the other coronaviruses," Dr Lin said.
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