US researchers spotted a segment of a protein on the outside of tumour cells that causes them to self-destruct when activated. Experts said the findings could see existing therapies turbo-charged.
US researchers spotted a 'switch' that causes cancer cells to self-destruct. The team now hopes to develop a treatment that targets this part of the cellA kill 'switch' which triggers the death of cancer cells could pave the way for new treatments, scientists say.
The pioneering therapy involves giving cancer patients specially-engineered T-cells to seek out and destroy tumours. Researchers at the UC Davis Comprehensive Cancer Center identified a section on the receptor that can activate the destruction process when targeted. While this treatment is effective against blood cancers, a minority of patients will see their cancer return. And it is not yet available for patients with solid tumours, such as breast, lung and bowel cancer.
However, some children with leukaemia and adults with lymphoma may get chimeric antigen receptor T-cell therapy.
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