Scientists call for standardization of allergy tests after trials show them to be unreliable

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Scientists call for standardization of allergy tests after trials show them to be unreliable
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Dr. Thimo Ruethers from James Cook University's Australian Institute of Tropical Health and Medicine (AITHM) and JCU's Tropical Futures Institute (TFI) in Singapore says that shellfish allergy affects up to 3% of the general population, is usually lifelong and commonly triggers anaphylaxis—a condition that leads to respiratory collapse and can be fatal. In Australia, shellfish allergy is the number one trigger of food-related fatal anaphylaxis.

"Skin prick testing is often the preferred first-line diagnostic approach. This involves a health worker placing a drop of allergen extract on the surface of the arm then pricking through it into the arm. If you are allergic to the allergen you will have a small, itchy swelling and a reddening of the skin after 10 to 15 minutes," said Professor Dianne Campbell from The Children's Hospital at Westmead, Sydney.

But Dr. Ruethers warned that widely utilized allergen extracts in commercial SPT kits are generally not standardized, limiting the diagnostic value of results.

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