Most of us who've reached middle age have noticed a slowing in memory and cognition, but scientists don't have a clear picture of the molecular changes that take place in the brain to cause it.
, a type of nervous system tissue that's integral to transmitting signals across the brain. The study also examined two treatments—caloric restriction and infusions of plasma from young mice—that affect certain regions of the brain, with the plasma appearing to slow the age-related decline.
"I saw this study as a way to explain that somewhat mysterious regional vulnerability," said Tony Wyss-Coray, Ph.D., a professor of neurology and neurological sciences who led the study that examinedWyss-Coray, the D.H. Chen Professor II at Stanford Medicine and the director of the Phil and Penny Knight Initiative for Brain Resilience at Stanford's Wu Tsai Neurosciences Institute, is the senior author of a paper describing the research.
"We cannot definitively say how gene expression changes in white matter affect memory and cognition. That would require moreand neurobiology work," Wyss-Coray said."But we know white matter is the wiring that connects the different brain regions together." During the study, the team explored two interventions—carloric restriction and injections of plasma from young mice—to evaluate whether they protected against the region-specific shifts in gene expression. Each intervention began when the mice were 19 months old and lasted four weeks.
Danmark Seneste Nyt, Danmark Overskrifter
Similar News:Du kan også læse nyheder, der ligner denne, som vi har indsamlet fra andre nyhedskilder.
Evaluating medical research using a new “diversity index” could promote better health outcomesScientific journals and research papers are evaluated by a metric known as their 'impact factor,' which is based on how many times a given paper is cited by other papers.
Læs mere »
Research helps to identify immunosuppressed people least likely to have COVID-19 antibodiesNew research involving the University of Southampton has identified which people with compromised immune systems are less likely to have COVID-19 antibodies—making them more vulnerable to a severe infection.
Læs mere »
New research expands insights into most adequate treatment for uterine descentWhen uterine descent requires surgery, various procedures exist. A randomized clinical trial of the two most common uterus-sparing procedures in 26 Dutch hospitals has now been published in JAMA. The results show that a hundred-year-old method shows better results after surgery than a more recently developed method. This is a relevant finding because both in the Netherlands and worldwide more women undergo the more recent method. There is also a group of patients who benefit more from the newer procedure.
Læs mere »
Victorian sewers not to blame for England’s pollution, research shows\n\t\t\tJournalists in 50+ countries follow the constant flow of money made and lost in oil & gas while\n\t\t\ttracking emerging trends and opportunities in the future of energy. Don’t miss our exclusive\n\t\t\tnewsletter, Energy Source.\n\t\t
Læs mere »
Research shows in-school occupational therapy creates positive education experiences for kids with autismStrong parent-school relationships are central to a child's learning, development, and well-being, yet when it comes to children with autism (ASD), it seems positive relationships are few and far between say UniSA researchers.
Læs mere »
Research shows how mosquito-transmitted viruses hijack host cells to promote infectionNew Cleveland Clinic research shows how mosquito-transmitted viruses – like Zika, West Nile, Yellow Fever and dengue viruses – hijack host cells to promote their own replication and infection.
Læs mere »