Scientists who gave men both scans and blood tests found nearly 50 of the 300 subjects had a normal PSA score, but an MRI showed signs of prostate cancer.
Using MRI scans rather than PSA tests to screen for prostate cancer could"significantly" reduce the number of men dying from the disease, researchers have said.is the most common cancer found in men and, at the moment, those aged over 50 can request a protein prostate-specific antigen test if they are experiencing symptoms.
But a study of more than 300 men who underwent both methods has found MRIs can detect cancers where PSA tests fail to. Nearly 50 of the 303 subjects in the Reimagine study had an MRI scan that indicated the presence of prostate cancer despite an average PSA score. Of the 48 people researchers identified, 32 had a PSA level below the current screening benchmark of three nanograms per millilitre and would not have been referred for further investigation.
After NHS assessment, 29 men were diagnosed with cancer that required treatment, 15 of whom had serious cancer and a PSA of less than 3ng/ml.
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MRI scans improve prostate cancer diagnosis in screening trialThe REIMAGINE study, published today in BMJ Oncology, is the first study to use MRI scans with prostate specific antigen (PSA) density to assess the need for further standard NHS tests. Of the 29 participants found to have serious prostate cancer, 15 had a 'low' PSA score that would have meant they were not referred for further investigation under the current system.
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Screening for prostate cancer could help save lives, study suggestsResearchers said current tests are linked to overdiagnosis and overtreatment of low-risk cancer.
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Screening for prostate cancer could help save lives, study suggestsResearchers said current tests are linked to overdiagnosis and overtreatment of low-risk cancer.
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