Personalised breast cancer screening could show death risk

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Personalised breast cancer screening could show death risk
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Researchers say breast cancer screening is vital, reducing deaths, but can sometimes detect tumours that are not harmful, which leads to unnecessary treatments

Researchers have developed a new model that predicts a woman’s likelihood of developing and then dying of breast cancer within a decade. Current breast cancer screening is vital, but can lead to overdiagnosis and unnecessary treatments, posing challenges to the NHS, researchers say.

“Risk-based approaches can also help make more efficient use of health service resources by targeting interventions to those most likely to benefit. We thank the many thousands of GPs who have contributed anonymised data to the QResearch database, without which this research would not have been possible.”

Data suggests that for every 10,000 UK women aged 50 years invited to breast screening for the next 20 years, 43 breast cancer deaths are prevented by screening, but 129 women will be overdiagnosed. With risk-based screening, the aim is to personalise screening depending on an individual’s risk, to maximise the benefits and minimise the downsides of such screening.

Identifying those at the highest risk of deadly cancers could improve screening. These women could be invited to start screening earlier, be invited for more frequent screenings, or be screened with different types of imaging, experts suggest.

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