‘Patients deserve better treatments for dementia’: NHS hopes for new Alzheimer’s drug ➡️ Crucial information on the side effects of Lecanemab are due to be released next week 🔴 PMGallagher1
An MRI brain scan. Early trial results have shown Lecanemab reduces the rate of decline among those with Alzheimer’s News on drug side effects crucial to the future of hundreds of thousands of Alzheimer’s sufferers in the UK is due to be released next week.
But there is a long road between a successful trial and a drug being made available on the NHS. Details on a potential major obstacle for Lecanemab will be released at theThe issue is the discovery that a prominent Lecanemab side effect can be small areas of swelling or bleeding on the brain. Most of the time this was asymptomatic. But about 3 per cent of the time there were symptomatic changes in the brain due to the drug.
If the side effects do require constant monitoring there is a chance the National Institute of Health and Care Excellence, which must approve the use of any new drugs on the NHS in England and Wales, could reject Lecanemab on cost grounds given the huge number people within the UK. It is also unclear exactly what difference the drug can make for patients.
Even if the side effects are shown not to be as severe as some medics fear, many hurdles remain before NHS patients might be able to not only access Lecanemab, but to be given it in ime to make a difference. Dr Coulthard said that the dementia patients she sees are usually well into the course of their illness and it is therefore too late for any treatment to help them.
“But under 1 per cent of patients seen in dementia clinics in the UK have that sort of precise diagnosis that actually show they have amyloid. So we’re seeing patients too late.” If a patients’ disease progresses to a moderate stage while on the waiting list, they will no longer be eligible for treatment. Only 5 per cent of patients eligible for the drug will be able to access it and most of these will be private cases, according to one estimate.
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