A National Institutes of Health-supported study suggests that adults with obesity may benefit from the use of extracorporeal membrane oxygenation (ECMO), an advanced form of breathing support, when in intensive care for respiratory failure.
Reviewed by Megan Craig, M.Sc.Aug 28 2023 ECMO's use was previously questioned for patients with obesity due to the belief that it may complicate treatment. However, the current findings, which published in the American Journal of Respiratory and Critical Care Medicine, show that patients with obesity who received ECMO for acute respiratory distress syndrome had lower mortality rates compared to patients with ARDS without obesity who received ECMO.
We hope that clinicians will consider the data from this study when making bedside decisions for ARDS patients with obesity instead of preemptively withholding this lifesaving therapy." Previous studies have found similar findings looking at data from patient registries and observational reviews. However, this study is the largest to date to assess ECMO survival outcomes among adults with obesity who have ARDS based on data from prospective studies and clinical trials, which better reflect real world clinical outcomes.
Related StoriesData for this review came from 440 patients who received intensive care for ARDS at hospitals in the United States, France, Australia, and Italy between 2012–2017. An additional 350 patients came from the Ventilation Management of Patients with Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome study, which took place at 23 intensive care units in 10 countries.
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