Noelin1-3 proteins essential for learning and memory formation in the mammalian brain

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Noelin1-3 proteins essential for learning and memory formation in the mammalian brain
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A German-American research team headed by Prof. Dr. Bernd Fakler from the Faculty of Medicine at the University of Freiburg demonstrated the major influence of Noelin1-3 proteins on learning and memory formation in the mammalian brain.

Reviewed by Megan Craig, M.Sc.Aug 18 2023 The results of this detailed study were recently published in the journal Neuron by the publisher Cell Press. The lead authors are Dr. Sami Boudkkazi and Dr. Jochen Schwenk, both members of the Institute of Physiology in Freiburg, and Dr. Naoki Nakaya from the National Institutes of Health in Bethesda, Maryland, USA.

“We have investigated AMPA receptors in the brains of mice with targeted deletions of the Noelin1-3 proteins. These knock-out animals were generated by our American partners led by Dr. Stanislav Tomarev from the National Institutes of Health, Bethesda, Maryland, USA,” says study leader Fakler.

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