More than 100 top scientists, including 15 Nobel laureates, have written an open letter calling for volunteers to be exposed to the coronavirus to assist with vaccine development.
They said so-called"human challenge trials" or"controlled infection trials" were of"vast importance" in speeding up the testing of the vaccines in development around the world."If challenge trials can safely and effectively speed the vaccine development process, there is a formidable presumption in favor of their use, which would require a very compelling ethical justification to overcome," the scientists wrote in the letter to Dr.
Challenge trials were used in early research with smallpox, yellow fever and malaria, which changed the course of global public health, according to WHO.Over the past 50 years, tens of thousands of consenting adult volunteers have safely undergone such trials under the oversight of research ethics committees, WHO reported. It said controlled infection trials could be ethically acceptable if they met certain criteria.
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