NHS England's Innovative Medicines Fund: A flawed approach to early access to new medicines

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NHS England's Innovative Medicines Fund: A flawed approach to early access to new medicines
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A new fund to fast-track patient access to potentially valuable new medicines may incentivize the pharmaceutical industry to develop high-priced drugs for rare diseases with weak evidence on clinical benefits.

Reviewed by Lily Ramsey, LLMAug 25 2023 A new fund to fast-track patient access to potentially valuable new medicines may incentivize the pharmaceutical industry to develop high priced drugs for rare diseases with weak evidence on clinical benefits.

The IMF operates on similar terms to the Cancer Drugs Fund , with a fixed annual budget of £340 million, equal to the CDF. Lead author Dr Aris Angelis, Assistant Professor in Health Economics at the Department of Health Services Research and Policy at LSHTM, said: "While we are broadly supportive of the eight guiding principles of the IMF, we believe their operationalization is described in insufficient detail and without fully leveraging the CDF experience.

The authors also question why the CDF and IMF schemes, also known as 'managed access' schemes, should only exist for medicines and no other types of interventions. "The need to consider non-medical interventions is particularly relevant in disease areas such as cancer, for which access to high quality radiation and surgical treatment are critical to improving outcomes," said co-author Dr Ajay Aggarwal, Associate Professor at LSHTM and clinical oncologist.

If the IMF is to successfully foster early access to clinically effective, safe and cost-effective medicines, say the authors, its operational details and mechanisms in place need to be carefully designed.

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