New test to diagnose 'the most common STI you've never heard of'

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New test to diagnose 'the most common STI you've never heard of'
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New test to diagnose trichomoniasis, 'the most common STI you've never heard of'

A quick, cheap test test has been developed to diagnose"the most common STI you've probably never heard of".- more than chlamydia , gonorrhoea or syphilis .

But even in asymptomatic people it can increase the likelihood of getting HIV, is linked to infertility and pregnancy complications in women, and may raise men's risk of prostate cancer. Like COVID-19 and pregnancy tests, the results are displayed in a window with a dot appearing if the antibody is present, indicating infection.Read more health news:Study lead author John Alderete, professor at WSU, said trichomoniasis"is the most common STI you've probably never heard of".

It is usually only diagnosed when people present with symptoms, which can include genital itchiness, abnormal discharge and a burning sensation during urination.

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Point-of-Care Diagnostic for Trichomonas vaginalis, the Most Prevalent, Non-Viral Sexually Transmitted InfectionPoint-of-Care Diagnostic for Trichomonas vaginalis, the Most Prevalent, Non-Viral Sexually Transmitted InfectionA point-of-care (POC) diagnostic is needed for both women and men to establish universal screening and surveillance for the number one, non-viral sexually transmitted infection (STI) caused by Trichomonas vaginalis. We developed a POC diagnostic for this STI using the MedMira Rapid Vertical Flow (RVF®) Technology test cartridge with a membrane that includes a Vertical procedural/reagent control line (referred to as CVL) and spotted with 1 µg of a 72.4-kDa truncated version of α-actinin called ACT::SOE3. This protein is a specific diagnostic target for antibody in sera of individuals with trichomoniasis. Serum antibody to ACT::SOE3 is a positive reaction with the test spot. Specificity of ACT::SOE3 was revealed with monoclonal antibodies (MAbs) generated to ACT::SOE3. Addition of negative control serum with MAb 67B reactive to ACT::SOE3 shows detection of both ACT::SOE3 and the CVL. Only positive sera of individuals had antibody reactive with ACT::SOE3 and detected the presence of the spot and the CVL. Negative control sera were unreactive with ACT::SOE3 and only showed the presence of the CVL. Importantly, to show proof-of-principle for POC application, ACT::SOE3 was detected with the positive patient sera spiked with whole blood. Finally, packaged cartridges stored with desiccant packs at 37 °C for one year gave identical results with the positive and negative human sera. Our results show the validity of this new POC serodiagnostic for this STI.
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