New breakthroughs by scientists at the National Physical Laboratory (NPL) are set to transform cancer treatment in the UK and worldwide.
NPL scientists have worked on a range of projects that are set to significantly improve the accuracy of a type of radiotherapy treatment called proton beam radiotherapy. The benefits of this therapy include more precise targeting of cancer tumors without damaging surrounding healthy tissue. It massively minimizes the unpleasant side effects of radiotherapy, particularly in the case of pediatric patients, including cardiac failure, pulmonary fibrosis, and secondary cancers.
With the PSPC, NPL ensures that cancer patients undergoing proton radiotherapy receive consistent and accurate radiation doses across different treatment facilities. This improves the chances of successfully treating the tumor and reduces variability in dose delivery to patients. Existing test materials produce large uncertainties in proton therapy dosimetry resulting in relative differences in “range” of up to eight percent. As such, these existing materials cannot be used to provide accurate quality assurance measurements for proton therapy dosimetry.
Identifying the ideal dose for new ultra-high dose FLASH radiotherapy technique Using pioneering measurement technology, NPL scientists measured and standardized the ideal optimal absorbed dose for a potentially revolutionary form of proton beam radiotherapy known as FLASH. Accurate dosimetry is essential to avoid errors that might result in a patient receiving an incorrect dose of radiation and less chance of successful treatment. Currently, any form of radiotherapy results in unwanted but unavoidable deposition of radiation to healthy tissue around the targeted tumor.
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