An enzyme that may help some breast cancers spread can be stopped with an antibody created in the lab of Cold Spring Harbor Laboratory Professor Nicholas Tonks.
Reviewed by Danielle Ellis, B.Sc.Oct 30 2023 With further development, the antibody might offer an effective drug treatment for those same breast cancers.
Disruptions in the addition or removal of phosphates can contribute to inflammation, diabetes, and cancer. Some disruptions can be corrected with kinase-blocking drugs. Many enzymes can be switched off with small molecules designed to latch onto and block the part of the enzyme that carries out its work. But that won't work for PTPs like PTPRD. So, alternative strategies are necessary.
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New antibody could target breast cancersAn enzyme that may help some breast cancers spread can be stopped with an antibody created in the lab of Cold Spring Harbor Laboratory Professor Nicholas Tonks. With further development, the antibody might offer an effective drug treatment for those same breast cancers.
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