Ahead of WorldAIDSDay2022 we spoke Dr. Larry Corey internationally renowned expert in virology, immunology, and vaccinedevelopment from fredhutch about his work within the field of HIV AIDS research
Interview conducted by Danielle Ellis, B.Sc.Nov 30 2022 Thought LeadersDr. Larry CoreyProfessor and President and Director EmeritusFred Hutch Cancer Center
How have you seen the field of HIV/AIDS research change in this time? How have patient outcomes changed? HIV is still a pandemic illness. We still have 1.4 million new infections each year. We have a growing number of people living with AIDS, and it is still a perfect storm. You acquire it subclinically, transmit it subclinically, and get it from people you don't suspect have it. We still need better prevention methods.
Patient outcomes for treatment have markedly changed. You can live normal lives. But we haven't made as many inroads in prevention. The reason is that we don't have a vaccine. When you look at how to prevent disease acquisition on a population basis, it's only been with a vaccine. So, as hard as it is, the vaccine effort must continue.
The HVTN's goal is to develop a safe, effective vaccine to prevent HIV globally. How close are we to actualizing this goal? From a global perspective, what would it mean to have an effective vaccine? We make these vaccines that elicit broadly neutralizing antibodies. If we do, we'll get there because we've already proven that broadly neutralizing antibodies can prevent HIV acquisition.
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