Insights into COVID-19's aftermath: 2-year study examines lasting health effects

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Insights into COVID-19's aftermath: 2-year study examines lasting health effects
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Researchers comprehensively assessed the risks and burdens of post-acute sequelae of coronavirus disease 2019.

By Pooja Toshniwal PahariaAug 28 2023Reviewed by Lily Ramsey, LLM In a recent study published in Nature Medicine, researchers comprehensively assessed the risks and burdens of post-acute sequelae of coronavirus disease 2019 in hospitalized and non-hospitalized settings for the acute phase of COVID-19 in two years post-infection.

Participants in the trial were tracked for two years to assess the hospitalization, mortality, and 80 pre-specified PASC outcome risks among hospitalized and non-hospitalized individuals. During follow-up, the researchers additionally assessed the link between SARS-CoV-2 infections and new-onset tumors as a negative control. COVID-19 was identified using polymerase chain reaction and SARS-CoV-2 antigen testing.

Within the PASC outcomes, 69% and 35% of outcomes turned non-significant two years post-infection among non-hospitalized and hospitalized patients, respectively, including risks of neurologic, cardiovascular, psychological, and renal outcomes.

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