Addressing neighborhood 'hotspots' where fewer than 60% of children receive first MMRvaccine on time QMUL BMJ_Open
We extracted sociodemographic and geographical data for each child, together with—for each child—all clinical events relating to MMR procedures. Documentation of the processing of MMR events can be found in
. Using access to calendar week, month and year of birth we derived a proxy date of birth combining the date of the first day of the week of the calendar week of birth with month and year of birth.We defined timely MMR vaccination as receipt of the first MMR vaccination between 12 and 18 months of age, which is consistent with NHS England’s definition of a timely MMR vaccination for the Quality and Outcomes Framework .
For children with a GP-recorded address with an associated LSOA in NEL, we plotted choropleth maps of the proportion of children receiving timely MMR vaccination in each cohort and the change in proportion between the two cohorts by LSOA, to visualise geographical clustering of MMR vaccination timeliness. LSOAs with fewer than 10 eligible children in either the pre-pandemic or pandemic cohorts were suppressed.
We conducted binary logistic regression to estimate the adjusted odds of timely MMR vaccination after adjustment for covariates. We tested an interaction between cohort and IMD quintile to assess whether COVID-19 had widened inequalities in timely vaccination. All analyses were conducted using Stata .We involved patients and the public in the communication of study results and dissemination within the local community using accepted principles from the UK Standards for Public Involvement.
Danmark Seneste Nyt, Danmark Overskrifter
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