How two structurally different lemon pectins modulate the gut microbiota Cell Diet FattyAcids Fermentation Fruit Gastrointestinal Microbiome ShortChainFattyAcids Vegetables Foods_MDPI USDA ChildrensPhila
By Dr. Priyom Bose, Ph.D.Dec 4 2022Reviewed by Benedette Cuffari, M.Sc. However, the results have been inconsistent, most likely because of differences in its chemical structure, which varies with its molecular weight and degree of esterification.Composition of Pectin The plant cell wall contains pectin , a complex structure comprising O-1 and O-4 linked galacturonic acids . It also contains three major units, namely, rhamnogalacturonan I , rhamnogalacturonan II , and homogalacturonan .
Gut microbiota can ferment pectin because of the presence of bacterial species that carry polysaccharide utilization loci and produce carbohydrate-active enzymes. These enzymes can break down pectin molecules and allow pectin to be used as a carbon source that subsequently ends in the production of SCFAs.
How do MW and DE Affect the Prebiotic Function of Lemon Pectin on the Gut Microbiota? Related StoriesA new Foods journal study has evaluated how MW and DE affect the prebiotic function of lemon pectin on the gut microbiota. An in vitro experimental design was used to understand the interactions between pectin and gut microbes. This experimental design successfully eliminated the multifarious interactions that occur between mammalian cells and gut microbiota in in vivo animal models.
Interestingly, it was observed that HMW-LDE elevated taxa within Lachnospiraceae in both donors. The finding of this study is in line with previous studies that reported elevated Lachnospiraceae following pectin treatment. For LMW-HDE lemon pectin, changes in the levels of Paraprevotella, Acidaminococcus, Psuedoramibacter, Alistipes, and Fusobacterium were found.
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