Neuroscientists at Scripps Research have identified brain circuits that make mammals want to eat more when they are exposed to cold temperatures.
Mammals automatically burn more energy to maintain normal body temperature when exposed to cold. This cold-activated increase in
One drawback of cold therapies is that humans' evolved responses to cold are not designed to cause weight loss . Cold, like dieting and exercise, increases appetite to counteract any weight-loss effect. In the study, Ye and his team set out to identify the brain circuitry that mediates this cold-induced appetite increase.
Using techniques called whole-brain clearing and light sheet microscopy, the researchers compared the activity of neurons across the brain during cold versus warm conditions. Soon they made a key observation: While most of the neuronal activity across the brain was much lower in the cold condition, portions of a region called the thalamus showed higher activation.
When the researchers artificially activated these neurons, the mice increased their food-seeking, but not other activities. Similarly, when the team inhibited the activity of these neurons, the mice decreased their food-seeking. These effects appeared only under the cold condition, implying thatprovide a separate signal that must also be present for appetite changes to occur.
Danmark Seneste Nyt, Danmark Overskrifter
Similar News:Du kan også læse nyheder, der ligner denne, som vi har indsamlet fra andre nyhedskilder.
Evaluating medical research using a new “diversity index” could promote better health outcomesScientific journals and research papers are evaluated by a metric known as their 'impact factor,' which is based on how many times a given paper is cited by other papers.
Læs mere »
Research helps to identify immunosuppressed people least likely to have COVID-19 antibodiesNew research involving the University of Southampton has identified which people with compromised immune systems are less likely to have COVID-19 antibodies—making them more vulnerable to a severe infection.
Læs mere »
New research expands insights into most adequate treatment for uterine descentWhen uterine descent requires surgery, various procedures exist. A randomized clinical trial of the two most common uterus-sparing procedures in 26 Dutch hospitals has now been published in JAMA. The results show that a hundred-year-old method shows better results after surgery than a more recently developed method. This is a relevant finding because both in the Netherlands and worldwide more women undergo the more recent method. There is also a group of patients who benefit more from the newer procedure.
Læs mere »
Victorian sewers not to blame for England’s pollution, research shows\n\t\t\tJournalists in 50+ countries follow the constant flow of money made and lost in oil & gas while\n\t\t\ttracking emerging trends and opportunities in the future of energy. Don’t miss our exclusive\n\t\t\tnewsletter, Energy Source.\n\t\t
Læs mere »
Research shows in-school occupational therapy creates positive education experiences for kids with autismStrong parent-school relationships are central to a child's learning, development, and well-being, yet when it comes to children with autism (ASD), it seems positive relationships are few and far between say UniSA researchers.
Læs mere »
Research shows how mosquito-transmitted viruses hijack host cells to promote infectionNew Cleveland Clinic research shows how mosquito-transmitted viruses – like Zika, West Nile, Yellow Fever and dengue viruses – hijack host cells to promote their own replication and infection.
Læs mere »