A research team co-led by City University of Hong Kong (CityU) and The University of Hong Kong (HKU) has recently made a significant advancement in spinal cord injury treatment by using genetically-modified human neural stem cells (hNSCs).
It also remarkably reduced glial scar accumulation, facilitating long-distance axon outgrowth. The team recorded a large number of axons extending more than 35mm at three months post-graft, while relatively less in number with shorter extensions to 25mm with non-modified neural stem cells.
The former recorded limb coordination, such as the capability to grasp a grid rung with correct placement, and the latter recorded stepping patterns to demonstrate their gait and fingertip motor ability.
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