Almost one in five Danes experiences depression during their lives. A new study from Aarhus University now shows that the genetic risk of depression can be linked to an increased genetic risk of other psychiatric diagnoses. The study has just been published in Nature Medicine.
The study shows for instance that people with hospital-treated depression and a high genetic predisposition to bipolar disorder are 32 times more likely to develop the disease than the rest of the general population.
Likewise, according to Anders Børglum, identifying people with depression and a high genetic risk of developing substance abuse could make the patient and the doctor aware of the issue. Preventative measures could then be initiated to prevent the development of substance abuse. The study shows that a total of 11,700 genetic risk variants can explain 90 percent of the heritability of depression, making depression one of the most complex and polygenic mental disorders. The majority of the risk genes still need to be identified.
Danmark Seneste Nyt, Danmark Overskrifter
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