Gargling with povidone-iodine may reduce salivary viral load in COVID-19 patients Coronavirus Disease COVID ClinicalTrial CoV Efficacy Pathogen Respiratory SciReports
Study: A prospective, randomized, open-label trial of early versus late povidone-iodine gargling in patients with COVID-19. Image Credit: CGN089 / Shutterstock
In the current prospective, open-level, randomized clinical trial, scientists have investigated whether gargling with povidone-iodine reduces salivary viral load and infectivity in a large number of COVID-19 patients. Each povidone-iodine intervention included one-time mouth washing and two-times gargling. In both groups, the patients performed povidone-iodine intervention four times a day . In the late intervention group, the patients performed the same procedure with water from day 2 to day 4.
Considering a sub-group of patients aged 40 – 49 years, a significantly higher viral clearance was observed in the early intervention group compared to that in the late intervention group.
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