A new drug offers a breakthrough world first treatment for Lipoprotein(a), a largely genetic form of cholesterol that increases the risk of heart attack and stroke, announced today by study lead Professor Stephen Nicholls, Director of the Monash University's Victorian Heart Institute and Victorian Heart Hospital.
High levels of Lipoprotein, known as Lp or spoken as 'LP little a', impact one in five people globally with no approved treatment currently on the market.
Professor Stephen Nicholls, renowned cardiologist and Director of Monash University's Victorian Heart Institute and the Victorian Heart Hospital at Monash Health, led the landmark research and trial, presented at the European Society of Cardiology Congress in Amsterdam today and published in JAMA. Common LDL lowering drugs such as statins don't have the same lowering effect on Lp. Being largely genetic, Lp is also difficult to control through diet, exercise and other lifestyle changes.
Professor Nicholls said the global research industry has been working on a targeted solution to treat elevated Lp for the past decade, but advancements so far have been in difficult to administer injection-based therapies that are not yet on the market.
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