Exploring T cell responses during COVID-19 breakthrough infection biorxivpreprint UniMelb COVID19 SARSCoV2 Infection BreakthroughInfection TCellResponse
By Bhavana KunkalikarDec 28 2022Reviewed by Aimee Molineux In a recent study posted to the bioRxiv* preprint server, researchers assessed the de novo and recall T cell responses during coronavirus disease 2019 breakthrough infection.
The team recruited 23 people with SARS-CoV-2 Delta or Omicron BA.1 or BA.2 breakthrough infection . Frequent longitudinal blood samples and nasal swabs were collected zero to 14 days post-symptom onset , with extra follow-up blood samples collected until day 44 PSO. Every tested individual submitted an average of nine samples, with 138 blood samples and 150 nasal swabs analyzed. All BTIs were minor and occurred on an average of 100 days after the last vaccination.
Results Antibodies eBook Compilation of the top interviews, articles, and news in the last year. Download a free copy The highest viral load occurred shortly after the onset of symptoms, and there was no considerable difference noted in the peak viral load among the three variants of concern . Analyzing the viral clearance rate as measured by linear regression, the decay rate for SARS-CoV-2 Delta outbreaks was notably faster than for Omicron.
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