Does the incidence of reported myocarditis or pericarditis after BNT162b2 vaccination vary by age, sex, and inter-dose interval among adolescents aged 12 to 17? JAMAPediatrics UofT uOttawa myocarditis pericarditis vaccine vaccination
By Neha MathurMar 3 2023Reviewed by Danielle Ellis, B.Sc. In a recent article published in JAMA Pediatrics, researchers conducted a population-based cohort study among 12 to 17-year-old adolescents in Ontario, Canada, to estimate the incidence of myocarditis or pericarditis after BNT162b2 vaccination. In addition, they determined whether these estimates varied with age, sex, and the interval between vaccine doses.
About the study In the present study, researchers pursued clinical information associated with reported cases of myocarditis or pericarditis in 12 to 17-year-old adolescents who received BNT162b2 vaccination. At present, Canada’s National Advisory Committee on Immunization recommends an eight-week interval between two vaccine doses.
Among these cases, the most reported symptom was chest pain, and 18% of them also reported a fever. In addition, these patients had elevated troponin levels; however, further investigations of the same were unfeasible owing to inadequate details for the troponin assay. Most individuals also had no regional wall motion aberrations or ventricular dysfunction. EDs handled most cases, so clearly, these cases were mild and resolved quickly.
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