A month after Yevgeny Prigozhin’s brief rebellion against Vladimir Putin, the mercenary leader pitched his paramilitary Wagner Group as the solution to the West African nation's security crisis. VeraMBergen reports on the Wagner Group’s growing reach
against Russian President Vladimir Putin, the mercenary leader was back to business as usual. After a military coup in Niger, Prigozhin pitched his paramilitary Wagner Group as the solution to the West African nation's security crisis."A thousand Wagner fighters are able to restore order and destroy terrorists," Prigozhin said on Telegram July 27,"preventing them from harming the civilian population.
This undated photograph provided by the French military shows three Russian mercenaries, in northern Mali. The Russian mercenary group that briefly rebelled against President Vladimir Putin’s authority has for years been a ruthless force-for-hire across Africa, protecting rulers at the expense of the masses.“The activities in Mali have dispelled the rumors that Wagner was pretty much packing up or diverting resources to Ukraine,” says Héni Nsaibia, an ACLED senior researcher.
In exchange, Wagner mercenaries trained local fighters, who became known as “Black Russians.” They primarily targeted civilians rather than fighting against rebel groups, according to ACLED. By 2020, Wagner fighters had started taking on a direct combat role, countering rebels seeking to overthrow the government of CAR President Faustin-Archange Touadéra, whose rivals have charged that he wants to make himself “president for life” under the protection of the Wagner army.
Of the hundreds of episodes of political violence ACLED has chronicled involving Wagner's operations in the country, the majority involve the targeting of civilians. The report cites Wagner for using tactics such as ejecting prisoners from aircraft and booby-trapping bodies. According to apublished in May, Malian troops along with “armed white men” who spoke an unknown language massacred more than 500 people in the village of Moura in March 2022—almost all of them civilians.
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Efficacy of low-dose risperidone in combination with sertraline in first-episode drug-naïve patients with schizophrenia: a randomized controlled open-label study - Journal of Translational MedicineObjective Despite advances in pharmacology, the treatment of schizophrenia (SZ) remains a challenge due to relapse after antipsychotic discontinuation and multiple adverse effects of antipsychotics. We hypothesized that a low dose of risperidone in combination with sertraline would reduce serious adverse effects without decreasing treatment response. This study aimed to examine the efficacy, safety, and tolerability of low-dose risperidone combined with sertraline to reduce risperidone dose and serious adverse effects in first-episode and medication-naive (FEMN) SZ patients. Methods A total of 230 patients with FEMN SZ were randomly assigned to receive low-dose risperidone in combination with sertraline (RS group) or regular-dose risperidone (control group). The Positive and Negative Syndrome Scale (PANSS), Hamilton Depression Rating Scale (HAMD), and Personal and Social Performance Scale (PSP) were assessed at baseline and the end of the first, second, third, and sixth months. In addition, serum prolactin levels and extrapyramidal symptoms were measured at baseline and follow-up. Results Repeated measures ANCOVA showed significant interaction effects of treatment by time on psychotic symptoms, as well as HAMD, PSP scores, prolactin levels, and extrapyramidal symptoms (all p | 0.05). Compared with the control group, the RS group had greater decreases in PANSS total score and its subscores and HAMD score (all p | 0.01) and a greater increase in PSP total score (p | 0.01). Notably, side effects were lower in the RS group relative to the control group. Improvements in HAMD and PANSS total scores, changes in prolactin levels and gender predicted improvements in PSP from baseline to month 6. Conclusions Our study suggests that low-dose risperidone in combination with sertraline was more effective for psychotic symptoms and psychosocial functioning, with significantly fewer adverse effects in patients with FEMN SZ. Trial registration number: ClinicalTrials.gov, NCT0407637
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