COVID-19 virus-human protein network provides new tools and strategies for screening host-targeting therapies NatureBiotech
The research focused on host-targeting therapies, which operate differently from other antivirals by disrupting the mechanisms viruses use to multiply and survive, rather than just blocking specific proteins within the cell. The research, published in, presents a network called an"interactome," the interactions between COVID-19 virus proteins and host cell proteins.
"Building a comprehensive network assists in targeting crucial protein-protein interactions instead of just proteins within the virus, offering promising host-targeting approaches for COVID-19 and future pandemics," says Feixiong Cheng, Ph.D., associate staff at the Genomic Medicine Institute."Existing drugs could be used as repurposable treatments through targeting the pathways viruses use to infect the human body and survive.
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