Heart attack patients who do not take daily aspirin have an elevated likelihood of recurrent myocardial infarction, stroke or death compared with those who consistently take the drug, according to research presented at ESC Congress 2023.
Our findings suggest that not taking aspirin as prescribed after a heart attack is linked to a higher risk of having another heart attack, a stroke or dying. We recommend that all patients who have had a heart attack stay adherent to their aspirin in accordance with guidelines until randomized controlled trials have proven otherwise, and clinical guidelines have been changed."
Aspirin is mandatory following a heart attack due its ability to prevent blood clot formation, and thus reduce the risk of a new heart attack or stroke. However, as treatment and diagnostic methods have advanced in recent decades, the prognosis after myocardial infarction has improved and the long-term effects of aspirin are now less evident.
Adherence to aspirin was evaluated at two, four, six and eight years after the heart attack. In Denmark, every time a patient picks up a prescription of aspirin, the number of tablets and date of collection are recorded in registries. Adherence to aspirin at each of the four time points was assessed as the proportion of days patients had their pills over the preceding two years.
Related StoriesThe study included 40,114 patients with a first-time heart attack. Adherence to aspirin progressively declined with each time point, from 90% at two years following the heart attack to 84% at four years, 82% at six years and 81% at eight years.
Danmark Seneste Nyt, Danmark Overskrifter
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