Antimicrobial coating reduces spread of SARS-CoV-2 on public transport Coronavirus Disease COVID SARSCoV2 Coating Antimicrobial PublicTransport biorxivpreprint UKHSA
By Dr. Priyom Bose, Ph.D.Oct 18 2022Reviewed by Benedette Cuffari, M.Sc. Several viruses are transmitted through direct contact with surfaces contaminated with body fluids or soiled hands of infected individuals. In addition, the deposition of aerosolized viral particles can also contaminate surfaces.
Background Although the risk of SARS-CoV-2 transmission after brief contact with a contaminated surface is low, it increases when individuals touch a higher number of contaminated surfaces. Therefore, viral transmission through fomites depends on several factors, including the density of individuals, number of contacts by the contaminated hand, and duration of stay within a venue, along with adherence to mitigation strategies, such as frequent hand washing and use of surface decontaminants.
There remains an urgent need for more research to elucidate optimal practices for the public transport sector to prevent viral infection through contaminated surfaces. In addition to enhanced cleaning measures, some transport operators in the United Kingdom have used antimicrobial coatings, which reduce surface bioburden and viral contamination.
Previous studies have reported the effectiveness of QAC-based products in industrial, healthcare, and domestic settings against SARS-CoV-2. In addition, these cationic detergents contain substantial varieties of chemical structures, thus making them suitable for a wide range of applications, such as the inactivation of viruses, bacteria, and yeast.
No antiviral activity was found for the Terluran armrest. This finding is significant, as the manufacturers claimed that the coating was effective on all materials. Furthermore, in the absence of interfering substances, contact times of at least 15 minutes are required to achieve less than 3log10 reductions.
Since the product was designed to be used alongside regular cleaning, the researchers assessed whether wiping could affect the efficacy of the coating. In the presence of FBS, wiping with a wet cloth did not resume the product's efficacy, thus indicating that wiping with a damp cloth likely removed the coating from the surface.
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