A high proportion of adults in Europe do not have protective antibody concentrations against diphtheria Eurosurveillanc diptheria antibodies vaccines vaccination immune immunisation booster publichealth
By Dr. Chinta SidharthanMay 1 2023Reviewed by Lily Ramsey, LLM In a recent study published in the Eurosurveillance Journal, researchers conducted a retrospective analysis of seroprotection against tetanus and diphtheria among residents in Austria following an increase in diphtheria cases since 2022 in Europe.
Although no diphtheria outbreaks have been reported among the general population of European Union countries, the low seroprotection increases the risk of disease outbreaks. Additionally, the extent of diphtheria toxoid and tetanus toxoid antibody waning was also examined for individuals who had antibody concentration measurements for two-time points since the last vaccination. Enzyme-linked immunosorbent assay was used to determine the concentrations.
When analyzed according to sex, males were seen to have 1.13 times higher seroprotection against diphtheria than females. Austria introduced childhood vaccination against diphtheria in 1945, and the occurrence of diphtheria in the general population had drastically reduced by the late 1960s.
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